Optimal Two and Three Stage Designs for Single-Arm and Two-Arm Randomized Controlled Trials with a Long-Term Binary Endpoint


[Up] [Top]

Documentation for package ‘OptInterim’ version 3.0.1

Help Pages

OptimInterim-package Optimal Two and Three Stage Designs with Time-to-event Endpoints Evaluated at a Pre-specified Time.
FixDes Construct a Single-stage Design for a time-to-event Endpoint Evaluated at a Pre-specifed Time Versus Either a Known Standard Control or a Randomized Comparative Control
np.OptimDes Optimal Two-Stage or Three-Stage Designs with User-specified Combined Sample Size or Study Length
OptimDes Construct Optimal Two-stage or Three-stage Designs with Time-to-event Endpoints Evaluated at a Pre-specified Time
OptimDesControl Set parameters controlling numerical methods for OptimDes and np.OptimDes
plot.OptimDes Plot efficiency of optimal two-stage or three-stage designs as a function of the total sample size or study length
print.OptimDes Print Objects Output By OptimDes
SimDes Simulation Studies for Two-Stage or Three-Stage Designs from function OptimDes
TestStage Statistical test for two-stage or three-stage designs from function OptimDes
weibPmatch Compute the shape or scale parameter for a Weibull distribution so it has a specified event-free rate at a specified time.
weibull.plot Plot Weibull Survival Curves