Drug Interaction Modeling Based on Loewe Additivity Following Harbron's Approach


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Documentation for package ‘drugCombo’ version 1.2.1

Help Pages

bootstrapCoefs Show estimated model parameters from all bootstrap iterations
checkerboardData Example checkerboard design drug combination data
contour.tauSurface Contour-plot method for "tauSurface" objects
fitModel Fit drug interaction index model according to Harbron's framework
fitPlot2d Plot 2d surface (slices) of observations and model fit
fitPlot3d Plot 3d surface of observations and model fit
getBootTaus Run nonparametric bootstrap on the interaction index model
getTauSurface Compute interaction index surface and confidence intervals
invL4 Inverse 4-parameter log-logistic (response-dose) function
plot.HarbronFit Plot method for 'HarbronFit' objects
plot.tauSurface Plot method for "tauSurface" objects
print.tauSurface Print method for "tauSurface" objects
rayData Example ray design drug combination data
tauPlot2d Plot estimated interaction index surface slice along one of the doses
tauPlot3d Plot 3d surface of interaction index estimates
unique.tauSurface Unique method for "tauSurface" objects